Many investigators believe that the first step in atherogenesis is the creation of atherosclerotic plaques and that infection by microorganisms is. Nutrition vol 28, issue 6, pages a1a4, 595714 june. In their longterm followup study of a large cohort of young people with low risk of cardiovascular mortality, abdullah et al 1 concluded that lowdensity lipoprotein cholesterol. Pdf how statistical deception created the appearance that statins. Serious bias in 20 year followup study of statin trial. We have provided a critical assessment of research on the reduction of cholesterol levels by statin treatment to reduce. By way of background, richard feinman is professor of biochemistry at the suny downstate medical center in new york, editor of the journal and one of the pioneers of the successful treatment of type 2 diabetes with a lowcarbohydrate, highfat diet. Uffe ravnskov circa 2005 uffe ravnskov born 1934 is a danish medical doctor, independent researcher, and a former assistant professor and medical practitioner in denmark and sweden. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. Inflammation, cholesterol levels, and risk of mortality. Safety, lifesaving efficacy of statins have been exaggerated. Cholesterollowering treatment may worsen the outcome of a covid. Uffe ravnskov,1 david m diamond,2 rokura hama,3 tomohito hamazaki,4 bjorn hammarskjold,5 niamh hynes,6 malcolm kendrick,7 peter h langsjoen,8 aseem malhotra,9 luca mascitelli,10 kilmer s mccully,11 yoichi ogushi,12 harumi okuyama, paul j rosch,14 tore schersten,15 sherif sultan,6 ralf sundberg16 to cite.
Harriet hall, md also known as the skepdoc, is a retired family physician who writes about pseudoscience and questionable medical practices. Uffe ravnskov, md, phd is a danish independent researcher and author. The bmj s news story on the followup study of the woscops trial says that total and cardiovascular mortality were considerably reduced in men allocated to the treatment. May 14, 2014 from table 2 and the references of their systematic analysis micha and colleagues seem to recommend replacing saturated fatty acids sfas with polyunsaturated fatty acids pufas to lower the risk of cardiovascular disease. The journal also covers toxicity issues, adverse reactions, pharmacoeconomics. Gorski, md, phd, facs is a surgical oncologist at the barbara ann karmanos cancer institute specializing in breast cancer surgery, where he also serves as the medical director of the alexander j. Published by new trends publishing inc,us 01092001 2001 isbn 10. Ravnskov s contention is that the dietheart idea is built on sand.
Weston prices appalling legacy sciencebased medicine. Exposing the fallacy that saturated fat and cholesterol cause heart disease. In 1973, together with his wife, he published a book, called the cholesterol controversy which summarized all the inconsistencies of the cholesterol idea. Fat and cholesterol dont cause heart attacks and statins. Lack of evidence that saturated fat causes cardiovascular disease. I wrote about the cholesterol skeptics in my book carbophobia now available free, full text online i think the issue was best summarized in a medical journal editorial entitled. At constant body weight, the replacement of saturated fat with other nutrients unequivocally lowers cholesterol concentrations. Lack of evidence that saturated fat causes cardiovascular.
Dr liu and colleagues 1 reported that among patients receiving dialysis, cholesterol levels and mortality were inversely associated among patients with. Malcolm kendricks the great cholesterol con are the most. Go to the edit tab and youll find a complete toolset to edit your pdf document. Pdf letter by ravnskov et al regarding article, longterm. American college of physicians guidelines on cholesterol. Reply to u ravnskov the american journal of clinical. This is disputed by uffe ravnskov who feels that the difference is significant, and points to rodent studies showing statin drugs cause cancer in animals. Grundy says that saturated fatty acids sfa are the main dietary cause of coronary heart disease chd dietary fat.
Reversing years of negative press on saturated fats, time. International cholesterol sceptics network reveals the flaws. Famous for questioning the scientific consensus regarding the lipid hypothesis. Dr liu and colleagues1 reported that among patients receiving dialysis, cholesterol levels and mortality were inversely associated among patients with chronic inflammation but were positively associated in those without inflammation. She headed a number of studies on the content and effects of trans fatty acids in america and israel and successfully challenged government assertions that dietary animal fat causes cancer and heart disease.
So the real truth is that statins have almost no real benefit in the very vast majority of users. Over two decades ago, william clifford roberts, md, editor of the american journal of cardiology, referred to statins as underused miracle drugs, which are to. Final nails for the the american institute of stress. Presented as a poster at the 18th international congress of clinical chemistry and laboratory medicine in kyoto, 2002. Huge amounts of money and manpower are wasted in the pursuit of blind paths, millions of healthy people are converted into patients and perhaps worse of all, new, more intellectually creative ideas are suppressed, either by the inventors themselves or by their colleagues. From table 2 and the references of their systematic analysis micha and colleagues seem to recommend replacing saturated fatty acids sfas with polyunsaturated fatty acids. Lack of evidence for recommended lowdensity lipoprotein. He leads us through the history of the concept in an interesting and readable way. In their longterm followup study of a large cohort of young people with low risk of cardiovascular.
It looks like we dont have any biography for uffe ravnskov yet be the first to contribute. Reversing years of negative press on saturated fats, time magazine has finally admitted defeat on this issue, reversing course and admitting that the war on fat was wrong. Safety, lifesaving efficacy of statins have been exaggerated, says scientist. Pdf on apr 30, 2019, uffe ravnskov and others published letter by ravnskov et al regarding article, longterm association of lowdensity lipoprotein cholesterol with. Read also martijn b katans response as well as a discussion about our correspondence by michael r eades and others. The finding that bacteria form biofilms within the majority of carotid arterial plaques is a further demonstration of the important role played by microorganisms in the etiology of atherosclerotic vascular disease 1. Fat and cholesterol are good for you steve parker, m. Evaluation of the effect on heart rate variability of a. To edit text, you just need to click the edit button to open the editing mode you can switch. Pdf letter by ravnskov et al regarding article, long.
Uffe ravnskov born 1934 is a danish medical doctor, independent researcher, and a former. The soft science of dietary fats, by gary taubes, in the march 30, 2001 issue of science, 1 exposes the shenanigans of the 1970s mcgovern senate committee staff and the. I wrote about the cholesterol skeptics in my book carbophobia now available free, full text online i think the issue was best summarized in a medical journal editorial entitled cholesterol myth club on par with flat earth society that read. They do more harm than good read uffe ravnskovs the cholesterol myths and malcolm. Rosenman, mdformer director of cardiovascular research, sri dr. Saturated fat does not affect blood cholesterol am j clin nutr 2006. How statistical deception created the appearance that. On criticism in biomedical research a tribute to uffe ravnskov. Letter by ravnskov et al regarding article, a longterm. Uffe ravnskov fodd 1934 ar en dansk oberoende forskare och forfattare. Apr 17, 2007 hayward and colleagues 1 rightly point out the extreme weakness of ecological comparisons among statin trials. Pinckney is an editor of four medical journals and former co editor of jama, the journal of the american medical association. How statistical deception created the appearance that statins are safe and effective in primary and secondary prevention of cardiovascular disease expert rev. Their concern is justified by the lack of dose response.
Here is an excerpt from the book the great cholesterol myth by jonny bowden ph. The journal also covers toxicity issues, adverse reactions, pharmacoeconomics, and societal concerns. Letter by ravnskov et al regarding article, longterm. Ravnskov, a founding member of the international network of cholesterol skeptics, takes all those positions and goes even further in his book, the cholesterol myths published by newtrends publishing. Studies of dietary fat and heart disease 22 february 2002 vol 295 science in his letter about the article the soft science of dietary fat news focus, g. Biofilms, lipoprotein aggregates, homocysteine, and arterial. Ancel keys, the mcgovern commission and other people with very big egos have played with our health and now we see the result. For many years, consensus committees and other evangelists have ignored or misquoted findings unsupportive of the idea that dietary therapy can reduce risk for coronary disease 1. Are high blood cholesterol levels in children a matter of concern. Another statin trial, care cholesterol and recurrent events, showed 1500 % increase in breast cancer among women in the statin treated group, explained as merely a statistical aberration. Fat and cholesterol dont cause heart attacks and statins are. Gorski, md, phd, facs is a surgical oncologist at the barbara ann karmanos cancer institute specializing in breast cancer surgery, where he also serves as the medical director of. In a sort of continuation of this line of thinking, this week ill turn my attention to one of the other most common characteristics of a crank, be he scientific crank i.
Biofilms, lipoprotein aggregates, homocysteine, and. Biochemistry at the suny downstate medical center in new york, editor of the. In their longterm followup study of a large cohort of young people with low risk of cardiovascular mortality, abdullah et al 1 concluded that lowdensity lipoprotein cholesterol ldlc and nonhighdensity lipoprotein cholesterol 160 mgdl is associated with a 50% to 80% increased relative risk of cardiovascular mortality. Vulnerable plaque formation from obstruction of vasa. For many years, consensus committees and other evangelists have ignored or misquoted. Hayward and colleagues 1 rightly point out the extreme weakness of ecological comparisons among statin trials. Werkzaam in verschillende ziekenhuizen in denemarken en zweden chirurgie, neurologie, radiologie, kindergeneeskunde en algemene geneeskunde 19681979. How the cholesterol myths are kept alive by uffe ravnskov, md, phd createspace, 2010 building cell walls and nerve fibers requires cholesterol. Walt comprehensive breast center, professor of surgery and oncology at the wayne state university school of medicine, and faculty of the graduate program in cancer biology. In recent years he has gained notice for questioning the scientific consensus regarding the lipid hypothesis. The finding that bacteria form biofilms within the majority of carotid arterial plaques is a further demonstration of the important role played by microorganisms in the. Hidden truth about cholesterollowering drugs page 5 medical doctors, drug manufacturers and nutritional supplement companies make billions of dollars browbeating us into believing that. Providing a forum for critical analysis of all aspects of safety, tolerability, efficacy, and therapeutic applications.
In their longterm followup study of a large cohort of young people with low risk of cardiovascular mortality, abdullah et al1 concluded that lowdensity lipoprotein cholesterol ldlc and nonhighdensity lipoprotein cholesterol 160 mgdl is. His writing clearly demonstrates the enormous depth and range of his reading on this subject. Their concern is justified by the lack of dose response between the degree of cholesterol lowering and the clinical 2, 3 or angiographic 4 outcome found in the trials where dose response was calculated by using individual data. Oct 31, 2017 the bmj s news story on the followup study of the woscops trial says that total and cardiovascular mortality were considerably reduced in men allocated to the treatment group at 20 year followup. Pdf dokumente bearbeiten mit pixelplanet pdf editor. On criticism in biomedical researcha tribute to uffe ravnskov. Ravnskov s measured and cleareyed analysis actually serves as a sledgehammer that breaks down barriers to healthy, sensible eating.
Ravnskovs suggestion that a reduction in the intake of saturated fat does not lower cholesterol is wrong. The content on this site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. Serious bias in 20 year followup study of statin trial the bmj. Uffe ravnskov, md, phd harumi okuyama, md, phd sherif sultan, md, phd to the editor.
Leo prize, uffe ravnskov, the cholesterol myths, rudolph. As will be seen, no studies support the notion that restricting fat reduces coronary morbidity or mortality. Mary enig and uffe ravnskov unlikely lipitor spokesmen two more unlikely spokesmen for the lipitor ad campaign include mary enig and uffe ravnskov. The controversy about cholesterol does not stem from ideological differences only. Implications of 4s evidence on baseline lipid levels. Ravnskov has now published approximately 58 letters to the editor. But dont expect more mainstream media to follow this repentance on saturated fats. Kand for ifragasatta vetenskaplig konsensus om lipid hypotesen. Several years of searching among editors and literature agents was unsuccessful. By uffe ravnskov md to suppress or distort information in science may produce many unfortunate consequences. Just click the edit page button at the bottom of the page or learn more in the biography submission guide.
676 771 361 1098 157 418 1381 598 3 1220 1265 418 394 221 1398 433 1054 967 894 1291 657 951 510 191 1060 53 337