For many years, consensus committees and other evangelists have ignored or misquoted findings unsupportive of the idea that dietary therapy can reduce risk for coronary disease 1. Huge amounts of money and manpower are wasted in the pursuit of blind paths, millions of healthy people are converted into patients and perhaps worse of all, new, more intellectually creative ideas are suppressed, either by the inventors themselves or by their colleagues. The controversy about cholesterol does not stem from ideological differences only. Implications of 4s evidence on baseline lipid levels. Biofilms, lipoprotein aggregates, homocysteine, and. Uffe ravnskov,1 david m diamond,2 rokura hama,3 tomohito hamazaki,4 bjorn hammarskjold,5 niamh hynes,6 malcolm kendrick,7 peter h langsjoen,8 aseem malhotra,9 luca mascitelli,10 kilmer s mccully,11 yoichi ogushi,12 harumi okuyama, paul j rosch,14 tore schersten,15 sherif sultan,6 ralf sundberg16 to cite. The content on this site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. Hidden truth about cholesterollowering drugs page 5 medical doctors, drug manufacturers and nutritional supplement companies make billions of dollars browbeating us into believing that. This is disputed by uffe ravnskov who feels that the difference is significant, and points to rodent studies showing statin drugs cause cancer in animals. Enig, phd, facn, cns, was an expert of international renown in the field of lipid chemistry. Fat and cholesterol are good for you steve parker, m. Ravnskov, a founding member of the international network of cholesterol skeptics, takes all those positions and goes even further in his book, the cholesterol myths published by newtrends publishing. Leo prize, uffe ravnskov, the cholesterol myths, rudolph. Pdf letter by ravnskov et al regarding article, long.
International cholesterol sceptics network reveals the flaws. She headed a number of studies on the content and effects of trans fatty acids in america and israel and successfully challenged government assertions that dietary animal fat causes cancer and heart disease. Go to the edit tab and youll find a complete toolset to edit your pdf document. The finding that bacteria form biofilms within the majority of carotid arterial plaques is a further demonstration of the important role played by microorganisms in the. Evaluation of the effect on heart rate variability of a. His writing clearly demonstrates the enormous depth and range of his reading on this subject. Inflammation, cholesterol levels, and risk of mortality. In recent years he has gained notice for questioning the scientific consensus regarding the lipid hypothesis. May 14, 2014 from table 2 and the references of their systematic analysis micha and colleagues seem to recommend replacing saturated fatty acids sfas with polyunsaturated fatty acids pufas to lower the risk of cardiovascular disease. Fodt 1934 i kobenhavn 1961 medicinsk embedseksamen ved kobenhavns universitet 19611967 forskellige ans. Here is an excerpt from the book the great cholesterol myth by jonny bowden ph. Ancel keys, the mcgovern commission and other people with very big egos have played with our health and now we see the result. The journal also covers toxicity issues, adverse reactions, pharmacoeconomics, and societal concerns. Providing a forum for critical analysis of all aspects of safety, tolerability, efficacy, and therapeutic applications.
In their longterm followup study of a large cohort of young people with low risk of cardiovascular mortality, abdullah et al1 concluded that lowdensity lipoprotein cholesterol ldlc and nonhighdensity lipoprotein cholesterol 160 mgdl is. The finding that bacteria form biofilms within the majority of carotid arterial plaques is a further demonstration of the important role played by microorganisms in the etiology of atherosclerotic vascular disease 1. Are high blood cholesterol levels in children a matter of concern. Malcolm kendricks the great cholesterol con are the most informative and most readable works youll find on the shoddy science that led to the lipid hypothesis and the bad science that keeps it alive today. Exposing the fallacy that saturated fat and cholesterol cause heart disease. Final nails for the the american institute of stress. Kand for ifragasatta vetenskaplig konsensus om lipid hypotesen. Mary enig and uffe ravnskov unlikely lipitor spokesmen two more unlikely spokesmen for the lipitor ad campaign include mary enig and uffe ravnskov. Dr liu and colleagues 1 reported that among patients receiving dialysis, cholesterol levels and mortality were inversely associated among patients with.
On criticism in biomedical research a tribute to uffe ravnskov. American college of physicians guidelines on cholesterol. In 1973, together with his wife, he published a book, called the cholesterol controversy which summarized all the inconsistencies of the cholesterol idea. Fat and cholesterol dont cause heart attacks and statins are. Uffe ravnskov, md, phd is a danish independent researcher and author. Walt comprehensive breast center, professor of surgery and oncology at the wayne state university school of medicine, and faculty of the graduate program in cancer biology. I wrote about the cholesterol skeptics in my book carbophobia now available free, full text online i think the issue was best summarized in a medical journal editorial entitled cholesterol myth club on par with flat earth society that read.
Malcolm kendricks the great cholesterol con are the most. Lack of evidence that saturated fat causes cardiovascular disease. Letter by ravnskov et al regarding article, a longterm. Ravnskov has now published approximately 58 letters to the editor. Nutrition vol 28, issue 6, pages a1a4, 595714 june. Famous for questioning the scientific consensus regarding the lipid hypothesis. As will be seen, no studies support the notion that restricting fat reduces coronary morbidity or mortality.
Vulnerable plaque formation from obstruction of vasa. From table 2 and the references of their systematic analysis micha and colleagues seem to recommend replacing saturated fatty acids sfas with polyunsaturated fatty acids. The bmj s news story on the followup study of the woscops trial says that total and cardiovascular mortality were considerably reduced in men allocated to the treatment. Apr 17, 2007 hayward and colleagues 1 rightly point out the extreme weakness of ecological comparisons among statin trials. How statistical deception created the appearance that. But dont expect more mainstream media to follow this repentance on saturated fats. Letter by ravnskov et al regarding article, longterm. Last week, i wrote one of my characteristically logorrheic meandering posts about what turns a scientist into a crank or a doctor into a quack. Harriet hall, md also known as the skepdoc, is a retired family physician who writes about pseudoscience and questionable medical practices. By uffe ravnskov md to suppress or distort information in science may produce many unfortunate consequences. Werkzaam in verschillende ziekenhuizen in denemarken en zweden chirurgie, neurologie, radiologie, kindergeneeskunde en algemene geneeskunde 19681979. Uffe ravnskov born 1934 is a danish medical doctor, independent researcher, and a former. How the cholesterol myths are kept alive by uffe ravnskov, md, phd createspace, 2010 building cell walls and nerve fibers requires cholesterol. Pinckney is an editor of four medical journals and former co editor of jama, the journal of the american medical association.
A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. Read also martijn b katans response as well as a discussion about our correspondence by michael r eades and others. In their longterm followup study of a large cohort of young people with low risk of cardiovascular mortality, abdullah et al 1 concluded that lowdensity lipoprotein cholesterol. Just click the edit page button at the bottom of the page or learn more in the biography submission guide. Grundy says that saturated fatty acids sfa are the main dietary cause of coronary heart disease chd dietary fat. Safety, lifesaving efficacy of statins have been exaggerated, says scientist.
He leads us through the history of the concept in an interesting and readable way. The journal also covers toxicity issues, adverse reactions, pharmacoeconomics. Biochemistry at the suny downstate medical center in new york, editor of the. Pdf dokumente bearbeiten mit pixelplanet pdf editor. Presented as a poster at the 18th international congress of clinical chemistry and laboratory medicine in kyoto, 2002. Cholesterollowering treatment may worsen the outcome of a covid. In their longterm followup study of a large cohort of young people with low risk of cardiovascular mortality, abdullah et al 1 concluded that lowdensity lipoprotein cholesterol ldlc and nonhighdensity lipoprotein cholesterol 160 mgdl is associated with a 50% to 80% increased relative risk of cardiovascular mortality. One part detective mystery, one part conspiracy theory, ravnskov tears through piles of medical studies digging towards the truth. Many investigators believe that the first step in atherogenesis is the creation of atherosclerotic plaques and that infection by microorganisms is. By way of background, richard feinman is professor of biochemistry at the suny downstate medical center in new york, editor of the. Ravnskov s measured and cleareyed analysis actually serves as a sledgehammer that breaks down barriers to healthy, sensible eating. It looks like we dont have any biography for uffe ravnskov yet be the first to contribute. In their longterm followup study of a large cohort of young people with low risk of cardiovascular. Gorski, md, phd, facs is a surgical oncologist at the barbara ann karmanos cancer institute specializing in breast cancer surgery, where he also serves as the medical director of.
Apr 30, 2019 pdf on apr 30, 2019, uffe ravnskov and others published letter by ravnskov et al regarding article, longterm association of lowdensity lipoprotein cholesterol with cardiovascular mortality. Their concern is justified by the lack of dose response between the degree of cholesterol lowering and the clinical 2, 3 or angiographic 4 outcome found in the trials where dose response was calculated by using individual data. Another statin trial, care cholesterol and recurrent events, showed 1500 % increase in breast cancer among women in the statin treated group, explained as merely a statistical aberration. Over two decades ago, william clifford roberts, md, editor of the american journal of cardiology, referred to statins as underused miracle drugs, which are to. Their concern is justified by the lack of dose response. To edit text, you just need to click the edit button to open the editing mode you can switch. Biofilms, lipoprotein aggregates, homocysteine, and arterial.
On criticism in biomedical researcha tribute to uffe ravnskov. The bmj s news story on the followup study of the woscops trial says that total and cardiovascular mortality were considerably reduced in men allocated to the treatment group at 20 year followup. Several years of searching among editors and literature agents was unsuccessful. Pdf on apr 30, 2019, uffe ravnskov and others published letter by ravnskov et al regarding article, longterm association of lowdensity lipoprotein cholesterol with. Uffe ravnskov, md, phd harumi okuyama, md, phd sherif sultan, md, phd to the editor. Reversing years of negative press on saturated fats, time magazine has finally admitted defeat on this issue, reversing course and admitting that the war on fat was wrong. Gorski, md, phd, facs is a surgical oncologist at the barbara ann karmanos cancer institute specializing in breast cancer surgery, where he also serves as the medical director of the alexander j. We have provided a critical assessment of research on the reduction of cholesterol levels by statin treatment to reduce. Published by new trends publishing inc,us 01092001 2001 isbn 10. In a sort of continuation of this line of thinking, this week ill turn my attention to one of the other most common characteristics of a crank, be he scientific crank i.
Reply to u ravnskov the american journal of clinical. The soft science of dietary fats, by gary taubes, in the march 30, 2001 issue of science, 1 exposes the shenanigans of the 1970s mcgovern senate committee staff and the. Uffe ravnskov fodd 1934 ar en dansk oberoende forskare och forfattare. Ravnskov s contention is that the dietheart idea is built on sand. Oct 31, 2017 the bmj s news story on the followup study of the woscops trial says that total and cardiovascular mortality were considerably reduced in men allocated to the treatment group at 20 year followup. They do more harm than good read uffe ravnskovs the cholesterol myths and malcolm.
Serious bias in 20 year followup study of statin trial. Ravnskovs suggestion that a reduction in the intake of saturated fat does not lower cholesterol is wrong. Serious bias in 20 year followup study of statin trial the bmj. Pdf letter by ravnskov et al regarding article, longterm. Lack of evidence that saturated fat causes cardiovascular. Dr liu and colleagues1 reported that among patients receiving dialysis, cholesterol levels and mortality were inversely associated among patients with chronic inflammation but were positively associated in those without inflammation. Saturated fat does not affect blood cholesterol am j clin nutr 2006. Safety, lifesaving efficacy of statins have been exaggerated. Lack of evidence for recommended lowdensity lipoprotein. The cholesterol and calorie hypotheses are both dead it.
Rosenman, mdformer director of cardiovascular research, sri dr. So the real truth is that statins have almost no real benefit in the very vast majority of users. I wrote about the cholesterol skeptics in my book carbophobia now available free, full text online i think the issue was best summarized in a medical journal editorial entitled. Fat and cholesterol dont cause heart attacks and statins.
Studies of dietary fat and heart disease 22 february 2002 vol 295 science in his letter about the article the soft science of dietary fat news focus, g. Uffe ravnskov circa 2005 uffe ravnskov born 1934 is a danish medical doctor, independent researcher, and a former assistant professor and medical practitioner in denmark and sweden. How statistical deception created the appearance that statins are safe and effective in primary and secondary prevention of cardiovascular disease expert rev. Pdf how statistical deception created the appearance that statins. Reversing years of negative press on saturated fats, time. Weston prices appalling legacy sciencebased medicine. For many years, consensus committees and other evangelists have ignored or misquoted.
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